What is iron overload?

The human body has no natural means to excrete iron, which may present problems for patients whose iron intake is increased (whether through blood transfusion or dietary uptake). Find out more…

What’s the pathophysiology of iron overload?

For many patients blood transfusions transfer quantities of iron that the body can’t excrete. For other patients, their blood disorder by itself increases the physiological uptake of iron from the diet. Find out more…

What are the consequences of iron overload?

High levels of iron in the blood can result in iron deposition in the liver, heart and endocrine organs. A wide range of diseases can develop. Find out more… 

How is iron overload diagnosed?

There are several tests that can be used, ranging from laboratory measures such as serum ferritin to magnetic resonance imaging. Find out more… 

How is iron overload managed?

You may already be familiar with iron chelation therapy, but you may not be aware of the evidence behind the guidelines. Find out more… 

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